Cryotherapy Versus Normal Saline Mouth Wash: Its Impact on Chemotherapy-Induced Oral Mucositis among Cancer Patients

Document Type : Original Article

Authors

1 Assistant lecturer, Medical-Surgical Nursing, Faculty of Nursing-Mansoura University

2 Assistant Professor of Medical-Surgical Nursing, Faculty of Nursing, Mansoura University

3 Prof. of Medical Oncology and Internal Medicine Faculty of Medicine - Mansoura University

4 medical surgical nursing department,f aculty of nursing,mansoura university

10.21608/mnj.2025.401329.1562

Abstract

Background: Oral mucositis (OM) is a severe consequence of chemotherapy, affecting 20%–40% of cancer patients, which can cause interruption or postponement of the treatment. Aim of the study: This study aimed to examine the impact of cryotherapy versus normal saline mouth wash on chemotherapy-induced oral mucositis (CIOM) among cancer patients. Method: A randomized controlled trial (RCT) research design was employed, involving a sample of 96 patients with cancer who were recruited from the Oncology Center at Mansoura University Hospital, Egypt, over six months. The study sample was divided randomly into three equal groups by a ratio of 1:1:1 (32) cancer patients for each. One tool used in this study consisted of two parts: part I, demographic characteristics & a health-relevant data sheet, as well as part II, the World Health Organization (WHO) mucositis scale. Results: Consistent with the WHO mucositis scale on the 14th and 21st day, the incidence of severe and moderate mucositis was lower in the cryotherapy group on assessment days, with P values of 0.005 and < 0.001, respectively. Conclusion and Recommendations: Oral cryotherapy (OC) is a key approach to reducing the severity and occurrence of OM among cancer patients. So, it's recommended that oncology nurses use oral cryotherapy (OC) in their daily care.

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